However, no studies have quantitatively compared nestin-positive MVD across AK, BCC, and SCC using standardized methods.<h4>Methods</h4>Immunohistochemistry for nestin, CD31, and CD34 was performed on 118 patient samples collected in 2015-2019 and diagnosed with AK, BCC, or SCC. The gene discussed is PECAM1; the disease is skin basal cell carcinoma.