For spindle cell/dedifferentiated melanoma, S100 showed a pooled OR of 161.23 (95% CI 24.55-1058.69), sensitivity of 0.95, and specificity of 0.94 (95% CI 0.85-0.97), while SOX10 yielded a pooled OR of 121.27 (95% CI 6.33-2323.34). Here, SOX10 is linked to melanoma.