CXCL8 and psychotic disorder: Pro-inflammatory and anti-inflammatory cytokines have been implicated, particularly interleukin (IL) 6, 8 and 10.<h4>Aim</h4>To investigate the association between serum inflammatory cytokines (IL-6, IL-8 and IL-10) and first-episode psychosis (FEP).<h4>Setting</h4>The study was at five clinical sites in KwaZulu-Natal, South Africa.<h4>Methods</h4>This study was an observational, cross-sectional sub-analysis of data derived from a larger longitudinal cohort study of individuals with FEP.