ADIPOQ and nutritional disorder: Analysis of adiponectin oligomers evidenced a significant down regulation of HMW and MMW isoforms in sarcopenic vs. pre-sarcopenic and non-sarcopenic patients.<h4>Discussion</h4>Our findings support the pivotal role of metabolic and nutritional disorders in muscle loss in CD patients and indicate adiponectin and phase angle as complementary biomarkers of sarcopenia.