The resulting labels were used to train, validate, and test 3 single-region models and multiregional models for trachoma detection.<h4>Main outcome measures</h4>The F1-score, area under the receiver operating characteristic curve (AUROC), and predicted TF prevalence were used to measure performance of all models on each of the test sets from Ethiopia, Niger, and Peru. Here, TF is linked to inclusion conjunctivitis.