Febrile patients exhibited significantly lower hemoglobin levels, platelet counts, serum calcium and phosphorus levels, but higher procalcitonin levels, elevated transaminase levels, higher γ-glutamyl transferase levels, and a prolonged prothrombin time (all <i>p</i> < 0.05).<h4>Conclusion</h4>The atypical clinical manifestations, lower positive rate of bacterial culture, and fewer abnormal laboratory findings pose a greater diagnostic challenge of afebrile brucellosis. The gene discussed is F2; the disease is brucellosis.