However, these effects disappeared both in the multivariable analysis and in the propensity-matched cohort.<h4>Conclusion</h4>The presence of a hemizygous <i>CDKN2A/B</i> deletion occurs more frequently in astrocytomas compared to oligodendrogliomas at the time of primary diagnosis. Here, CDKN2A is linked to astrocytoma (excluding glioblastoma).