GPT and Gingival bleeding: Secondary objectives included pharmacokinetics/pharmacodynamics parameters, and immunogenicity.<h4>Results</h4>Among 50 enrolled patients, the most common treatment-related adverse events (TRAEs) were aspartate aminotransferase elevation (20.0%), gingival bleeding (18.0%), alanine aminotransferase elevation (14.0%), rash (14.0%), and proteinuria (14.0%).