The Traf2- and Nck-interacting kinase (TNIK) is a regulator of Wnt/β-catenin signaling and has been implicated in the progression of several cancers, but its role in MB remains unclear.<h4>Methods</h4>TNIK expression was evaluated using publicly available MB transcriptomic datasets, mass spectrometry based proteomic data, and immunohistochemical analysis of a MB tissue microarray. This evidence concerns the gene TNIK and cancer.