STAT3 and non-small cell lung carcinoma: Western blotting results suggested that the antitumor effects of bruceine D might be mediated by the inhibition of the phosphorylation and nuclear translocation of STAT3.<h4>Conclusion</h4>Bruceine D exerts a strong inhibitory effect on NSCLC <i>in vitro</i> and <i>in vivo</i>.