In addition, a meta-analysis of previously published studies was performed to evaluate the overall association of these polymorphisms with cancer risk.<h4>Results</h4>The PPAR-γ rs1801282 C>G variant showed a significant association with NSCLC risk in both the dominant (adjusted OR = 6.74, p < 0.001) and allelic models (adjusted OR = 6.10, p = 0.001). This evidence concerns the gene PPARG and non-small cell lung carcinoma.