TRPV1 and acute myocardial infarction: Based on an experimental model of acupuncture at Neiguan (PC6) for intervening in acute myocardial infarction (AMI), this study aimed to 1) investigate whether acupuncture-induced local muscle contraction at the PC6 acupoint mediates the therapeutic effect of acupuncture, and 2) explore the initiation mechanism of acupuncture's effect from the perspective of transient receptor potential vanilloid 1 (TRPV1).<h4>Methods</h4>Sprague-Dawley (SD) rats were used to establish the AMI model via ligation of the left anterior descending coronary artery (LAD).