The glucocorticoid-associated risk decreased as the log2(EASIX) level increased (p < 0.001).<h4>Conclusion</h4>It found the positive association between log2(EASIX) levels and risk of mortality in critically ill patients suffering from AKI, particularly in those with decreased age or APS III, elevated albumin, and those characterized by mild AKI, or absence of CKD, sepsis or CRRT. This evidence concerns the gene ALB and chronic kidney disease.