Significant associations were found between adverse outcomes and abnormal SGOT (χ2=6.499, p=0.011), SGPT (χ2=8.500, p=0.004), and bilirubin (χ2=8.300, p=0.004), whereas SUA levels were not significantly associated with outcomes (p=0.115).<h4>Conclusion</h4>Hyperuricemia is common in pediatric complicated malaria and may reflect infection-related inflammation. The gene discussed is GPT; the disease is hyperuricemia.