GLP1R and cardiac transplant: We therefore performed a systematic review and meta-analysis of observational studies to evaluate metabolic, renal, and safety outcomes associated with GLP-1 RA therapy in adult heart transplant recipients.<h4>Methods</h4>Using a prespecified protocol registered with PROSPERO (CRD420251243172), we conducted a systematic review and meta-analysis of observational studies published in PubMed, Embase, Cochrane CENTRAL, and Scopus through January 31, 2025, evaluating GLP-1 RA therapy in adult heart transplant recipients.