The microRNA in SBELNs regulates calcium ion homeostasis through the miR159a/CNGA1 axis, thereby alleviating MG-induced intracellular calcium overload, mitochondrial damage, excessive ROS, and overactivation of the NF-κB inflammatory pathway.<h4>Conclusions</h4>This article expounds that SBELNs alleviate lung injury caused by MG infection by regulating calcium homeostasis. The gene discussed is NFKB1; the disease is myasthenia gravis.