Biological testing confirmed the ability of <b>1</b> to induce a mixed, non-lethal stress response in human U87-MG glioblastoma cells; analysis of stress markers by qRT-PCR revealed early upregulation of superoxide dismutase 1 (SOD1) and C/EBP-homologous protein (CHOP) relative to the control. The gene discussed is DDIT3; the disease is glioblastoma.