TRBC2 and neoplasm: Analogous to the detection of kappa/lambda light chains for the diagnosis of B-cell/plasma cell neoplasms in human clinical practice, our TCRβ1/2 diagnostic assay has the potential to transform veterinary diagnostic workflows.<h4>Methods</h4>We identified and confirmed the sequences of the relevant <i>TRBC1</i> and <i>TRBC2</i> sequences in both cats and dogs, focusing on the 3' untranslated region (UTR), where there is the least sequence homology between <i>TRBC1</i> and <i>TRBC2</i>.