Transcriptional Reprogramming of Cancer Metabolism: &lt;i&gt;Tricholoma terreum&lt;/i&gt; Inhibits Nucleotide Biosynthesis and Energy Flux in MCF-7 Cells by Downregulating &lt;i&gt;DHFR&lt;/i&gt;, &lt;i&gt;TK1&lt;/i&gt;, and &lt;i&gt;ENO1&lt;/i&gt;. The gene discussed is TK1; the disease is cancer.