Six ferroptosis-related genes (<i>SLC7A11</i>, <i>GPX4</i>, <i>FTH1</i>, <i>NQO1</i>, <i>NFE2L2</i>, <i>SQSTM1</i>) demonstrated consistent upregulation across all breast cancer subtypes, with higher expression observed in more aggressive tumors. The gene discussed is NFE2L2; the disease is breast cancer.