The rs7603052 polymorphism in <i>PDCD1</i> and rs17718883 in <i>CD274</i> were significantly associated (<i>p</i> = 0.033 and <i>p</i> = 0.043 respectively) with PD-L1 expression in tumor-infiltrating immune cells (TIICs). The gene discussed is CD274; the disease is neoplasm.