This descriptive study aimed to evaluate BAP1 immunohistochemical expression in a Croatian enucleation-based UM cohort, characterize its associations with clinicopathological parameters, and contextualize the findings within the published literature.<h4>Methods</h4>Formalin-fixed, paraffin-embedded tumor tissue from 58 consecutive patients with primary choroidal and ciliary body melanoma treated with enucleation at University Hospital Centre Zagreb (2006-2016) was analyzed immunohistochemically for BAP1 nuclear expression. This evidence concerns the gene BAP1 and malignant ciliary body melanoma.