TGFB1 and hypersensitivity pneumonitis: At day 14, Nlrp3 deficiency reduced persistent Siglec-F<sup>+</sup> neutrophils and broadly reduced airway inflammatory cytokines, accompanied by decreased lung damage, alveolitis, collagen deposition, fibrotic nodule expansion, and α-SMA expression, independent of detectable TGFβ changes.