Finally, <i>in vivo</i> studies showed that KRT7-AS knockdown inhibited tumor growth and modulated the expression of ferroptosis-related proteins by elevating ACSL4 and reducing GPX4.<h4>Conclusions</h4>These findings suggest that KRT7-AS has potential as a diagnostic biomarker for ovarian cancer. This evidence concerns the gene ACSL4 and ovarian carcinoma.