<h4>Background</h4>The NLRP3 inflammasome is a multiprotein complex of the innate immune system that mediates the maturation and secretion of interleukin-1β (IL-1β) and plays a pivotal role in the pathogenesis of chronic inflammatory diseases, including asthma, metabolic disorders, and autoimmune diseases. Here, NLRP3 is linked to Other metabolic disease.