OCLN and hereditary elliptocytosis: Conditioned media were collected and applied to human intestinal myofibroblasts (HIMF) from healthy and inactive CD ileum for 24 hours to assess proinflammatory and profibrotic gene expression.<h4>Results</h4>T+I exposure induced epithelial damage and cell death in CDiE, while reducing proliferation and decreasing occludin and F-actin expression in both HE and CDiE.