RETNLB and neoplasm: Univariate and multivariate prognostic analyses demonstrated that the risk model serves as an independent prognostic factor, and both the CCRG prognostic model and signature genes showed a significant correlation with the tumor immune microenvironment (TIME).<h4>Conclusion</h4>The CCRG risk model proposed in this study can accurately and stably predict the prognosis of DLBCL patients and is closely associated with the TIME, providing new targets and theoretical support for DLBCL patients.