Furthermore, LD analysis revealed no significant haplotype blocks in this population.<h4>Conclusion</h4>This study provided the first population-specific data on <i>TOLLIP</i> and <i>MUC5B</i> genotypes in Indian patients with ILD, highlighting genotype-driven variation in IFN-γ and distinct allele-frequency patterns compared to Western cohorts. Here, MUC5B is linked to interstitial lung disease.