Histological and immunohistochemical analyses were performed to assess morphological changes and marker expressions α-SMA, S100A4, and CD36 in CAAs.<h4>Results</h4>CAAs exhibited features consistent with dedifferentiation toward a myofibroblast-like phenotype, marked by expressing α-SMA and S100A4, indicators of myofibroblasts and tumor-associated fibroblasts. This evidence concerns the gene ACTA1 and neoplasm.