Higher proportions of FAP<sup>+</sup>, FAP<sup>+</sup>CAV1<sup>+</sup>, and FAP<sup>+</sup>CPXM2<sup>-</sup>CAV1<sup>+</sup> cells were associated with poorer overall survival (OS).<h4>Conclusions</h4>These findings suggest that CAV1 and CPXM2 are differentially expressed in GC and associated with patient prognosis, highlighting them as potential candidates for further functional investigation in the context of GC progression. This evidence concerns the gene CAV1 and gastric cancer.