DLEU1 and cancer: Additionally, we systematically reviewed and summarized the reported functional roles and molecular mechanisms of DLEU1 over the past five years.<h4>Results</h4>This meta-analysis, incorporating nine studies with a total of 938 cancer patients, demonstrated that elevated DLEU1 expression was significantly associated with shortened overall survival and adverse clinicopathological features, including lymph node metastasis and advanced TNM stage.