This study aims to determine UTI prevalence and identify risk factors in elderly T2DM patients using SGLT2 inhibitors, to enhance treatment strategies and patient safety.<h4>Methods</h4>A retrospective cohort study was conducted at two hospitals to evaluate UTI prevalence and predictors in elderly T2DM patients treated with SGLT2 inhibitors. Here, SLC5A2 is linked to bacterial urinary tract infection.