This study aims to determine UTI prevalence and identify risk factors in elderly T2DM patients using SGLT2 inhibitors, to enhance treatment strategies and patient safety.<h4>Methods</h4>A retrospective cohort study was conducted at two hospitals to evaluate UTI prevalence and predictors in elderly T2DM patients treated with SGLT2 inhibitors. The gene discussed is SLC5A2; the disease is type 2 diabetes mellitus.