Patients with vitiligo presented higher circulating levels of IFN-λ1 and IL-1b and ratios of IFN-λ1/IL-10 and IL-6/IL-10 (<i>p</i> < 0.05, <i>p</i> < 0.05, <i>p</i> < 0.001, and <i>p</i> < 0.01, respectively). The gene discussed is IL1B; the disease is vitiligo.