reuteri</i> directly degrades TCA, and decreased TCA levels restored the effector functions of CD4<sup>+</sup> and CD8<sup>+</sup> T cells.<h4>Conclusions</h4>This study demonstrates that BCV remodels the gut microbiota and enhances anti-tumor immunity by regulating the <i>L. The gene discussed is CD8A; the disease is neoplasm.