The Prognostic Value of the CD8&lt;sup&gt;+&lt;/sup&gt;PD-1&lt;sup&gt;+&lt;/sup&gt;/CD4&lt;sup&gt;+&lt;/sup&gt;PD-1&lt;sup&gt;+&lt;/sup&gt; (PERLS) Ratio for Leukemic Transformation in MDS. The gene discussed is CD4; the disease is myelodysplastic syndrome.