This study aimed to evaluate the expression and promoter methylation status of <i>AURKA</i>, <i>AURKB</i>, and <i>AURKC</i> and their regulatory genes, <i>AURKAIP1</i>, <i>E2F1</i>, and <i>E2F4</i> in AML. Here, AURKA is linked to acute myeloid leukemia.