TRIM26 and hepatocellular carcinoma: AUCell was used to assess TRIM26-pathway associations within specific cell types.<h4>Results</h4>TRIM26 was significantly upregulated in HCC tissues, and its high expression correlated with enrichment of oncogenic pathways including Wnt/<i>β</i>-catenin, G2/M checkpoint, and TGF-<i>β</i>.