APOE and dementia: No association between TBI and tau was identified in a subset with tau PET, and no TBI-amyloid correlations were observed among symptomatic participants (CDR>0; n=64) suggesting a ceiling effect of pathology once clinical dementia is present.<h4>Conclusions</h4>History of remote TBI-LOC is linked to elevated amyloid PET levels in later life, particularly among APOE ε4 carriers with a CDR=0.