CCL2 and oral cavity squamous cell carcinoma: Conversely, patients with high CCL2 expression in OSCC and decreased postoperative serum CCL2 exhibited the best disease-free and overall survival (P < 0.05).<h4>Conclusion</h4>The expression level of chemokine CCL2 in oral squamous cell carcinoma was significantly correlated with strong tumor invasiveness and poor prognosis.