Hyperglycaemia was induced in C57BL/6J mice by streptozotocin treatment, and the mice were randomly divided into Saline, APAP, APAP + NAC, and APAP + MgIG groups.<h4>Results</h4>The data demonstrated that APAP administration elicited pronounced histopathological injury and markedly upregulated serum transaminases (ALT and AST). Here, GPT is linked to Hyperglycemia.