Comparison between the positive and negative groups revealed that patients in the positive group had a significantly earlier age at onset (<i>p</i> < 0.05), a higher frequency of status epilepticus (<i>p</i> < 0.05), and a higher rate of developmental delay after onset (<i>p</i> < 0.001).<h4>Conclusion</h4>Febrile sensitivity-related epilepsy in children is primarily caused by <i>SCN1A</i>, <i>PCDH19</i>, and <i>ADGRV1</i> mutations, manifesting mainly as Dravet syndrome and PCDH19-related epilepsy. This evidence concerns the gene PCDH19 and epilepsy.