VEGFA and diabetic macular edema: PURPOSE: To (1) evaluate long-term real-world anatomical and functional outcomes after implantation of a sustained-release fluocinolone acetonide (FAc) implant in eyes with diabetic macular edema (DME) and (2) to assess the influence of prior anti–vascular endothelial growth factor (anti-VEGF) and corticosteroid exposure on treatment response and durability.