RNA-seq data revealed a cis correlation of cg00036588 with FAM83C (false discovery rate [FDR]=3.3 × 10<sup>-4</sup>) and EIF6 (FDR=0.13) in skeletal muscle.<h4>Conclusions/interpretation</h4>Our study identified two epigenetic markers as likely to be causal for type 2 diabetes in West African populations. This evidence concerns the gene EIF6 and type 2 diabetes mellitus.