IGF1 and Marchiafava-Bignami disease: A multivariate linear regression analysis was performed to assess PEW as an independent predictor of height velocity after adjusting for metabolic acidosis, GH/IGF-1 axis resistance and CKD-MBD; Spearman correlation and logistic regression analyses were conducted to explore the association between inflammatory markers (hs-CRP) and PEW.<h4>Results</h4>The prevalence of PEW was 30.6%, increasing with CKD severity: 0% (stage 3), 25.9% (stage 4), 39.7% (stage 5 non-dialysis), and 20.0% (stage 5D).