However, the average secretion levels of SDF-1, IL-10, and VEGF in the treatment group on day 7 (P.7) were lower than those on day 3 (P.3).<h4>Conclusion</h4>Secretomes from MSC cultures have great potential as an alternative therapy for xerostomia or other disorders caused by ionizing radiation, serving as a cell-free therapy. This evidence concerns the gene CXCL12 and xerostomia.