Blood loss, coagulopathy (activated partial thromboplastin time [aPTT], FII, FV, FVIII, FX, thrombin-antithrombin [TAT], and fibrinogen), and fibrinolysis (tissue-type plasminogen activator, plasmin-α2-antiplasmin complexes, and D-dimer) were analyzed 60 minutes after LL. This evidence concerns the gene F8 and blood coagulation disease.