<h4>Objective</h4>The aim of this study was to evaluate the levels of nuclear factor erythroid 2 related factor 2, tumor necrosis factor alpha, interleukin-40, and endorepellin in patients undergoing coronary artery bypass grafting and explore their potential diagnostic roles.<h4>Methods</h4>The study involved 43 coronary artery disease patients undergoing coronary artery bypass grafting and 43 age- and sex-matched healthy controls. This evidence concerns the gene NFE2L2 and coronary artery disorder.