<h4>Objective</h4>The aim of this study was to evaluate the levels of nuclear factor erythroid 2 related factor 2, tumor necrosis factor alpha, interleukin-40, and endorepellin in patients undergoing coronary artery bypass grafting and explore their potential diagnostic roles.<h4>Methods</h4>The study involved 43 coronary artery disease patients undergoing coronary artery bypass grafting and 43 age- and sex-matched healthy controls. The gene discussed is HSPG2; the disease is coronary artery disorder.