Statistical analyses were conducted using SPSS v25.0, with significance set at p<0.05.<h4>Results</h4>Nuclear factor erythroid 2 related factor 2 levels were significantly reduced, while tumor necrosis factor alpha and interleukin-40 were elevated in coronary artery disease patients (p<0.001, p=0.003, p=0.001). Here, C17orf99 is linked to coronary artery disorder.