HSPG2 and coronary artery disorder: Interleukin-40 may serve as a novel inflammatory biomarker; endorepellin's unchanged levels suggest localized vascular effects.<h4>Conclusion</h4>Nuclear factor erythroid 2 related factor 2, tumor necrosis factor alpha, and interleukin-40 emerged as significant biomarkers reflecting the inflammatory and oxidative stress mechanisms associated with coronary artery disease.