The predictive efficacy of GNRI was assessed using the receiver operating characteristic (ROC) curve.<h4>Results</h4>Compared to the non-osteoporosis group, patients in the osteoporosis group were significantly older and had significantly lower levels of GNRI, BMI, lumbar spine T-score, total protein, albumin, uric acid, albumin-corrected calcium, serum phosphorus, and 25-hydroxyvitamin D (all <i>p</i> < 0.05). Here, ALB is linked to osteoporosis.