SMC-SGK1-KO<sup>+/-</sup> +AAA mice showed significant reductions in radial strain (<i>p</i> = 0.0011) and distensibility (<i>p</i> = 0.0233) with a modest, but significant, increase in PPV (<i>p</i> = 0.0148).<h4>Conclusions</h4>SGK-1 inhibition attenuated AAA growth and preserved vascular function. This evidence concerns the gene SGK1 and triple-A syndrome.