Whole genome sequencing was conducted on 180 individuals who also had cytokine profiling.<h4>Results</h4>We found that ~25% of DCM patients had a CD4+ T-cell compartment that was abnormally skewed toward a Th2 phenotype, and Th2 skewing was highly correlated with male sex. The gene discussed is CD4; the disease is familial dilated cardiomyopathy.